Since 1947 (As Metafolin 1,000 MCG) Bio-Active Form Gluten, Wheat & Dairy Free Suitable For Vegans Certified Gluten Free Dietary Supplement Kosher ParveFolic Acid must first be converted to its active form by a series of biochemical steps before it is able to be used by the body. Metafolin (L-methylfolate) requires no conversion because it is bio-identical to the bio-active form. In other words, it is 'body-ready'. This can be useful for individuals whose bodies have difficulty converting folic acid to its active form. The active folate in this formulation promotes heart health. It also supports a healthy nervous system and the formation of healthy red blood cells.